Fluid Management Findings

Key Findings from Publications:

  • Therapy guided by Relative Plasma Volume (RPV) slope may serve as a valid tool to better achieve target weight using augmented reduction therapy among hemodialysis patients.1
  • RPV monitoring yields information that is prognostically important and independent of several risk factors including UF volume, aggressiveness of UF and interdialytic ambulatory blood pressure.2
  • RPV monitoring can assist in better achieving target weight.3
  • RPV has been used to find the best compromise between a high ultrafiltration rate and the prevention of intradialytic symptoms.1,4,5,6,7,8


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1. Sinha AD, Light RP, Agarwal R: "Relative Plasma Volume Monitoring During Hemodialysis Aids the Assessment of Dry Weight." Hypertension 55 (2010): 305-3110.
2. Agarwal, R. "Hypervolemia is Associated With Increased Mortality Among Hemodialysis Patients." Hypertension 56 (2010): 512-517.
3. Agarwal, R, Alborzi, P, Satayan, S. Light RP "Dry-weight Reduction in Hypertensive Hemodialysis Patients (DRIP): A Randomized , Controlled Trial." Hypertension 53 (2009): 500-507.
4. Rodriguez HJ, Domenici R, Diroll A, Goykhman I. "Assessment of Dry Weight by Monitoring Changes in Blood Volume During Hemodialysis using Crit-Line." Kidney Int 68 (2005): 854-861.
5. Goldstein S, Smith C, Currier H. "Non-invasive Interventions to Decrease Hospitalization and Associated Costs for Pediatric Patients Receiving Hemodialysis." JASN 14 (2003), 2127-2131.
6. Michael M, Brewer ED, Goldstein SL. "Blood Volume Monitoring to Achieve Target Weight in Pediatric Hemodialysis Patients" Pediatri Nephrol 19 no. 4 (2004) 432-437.
7. Reddan, DN, Szczech LA et al. "Intradialytic Blood Volume Monitoring in Ambulatory Hemodialysis Patients: A Randomized Trial" J Am Soc Nephrol 16 (2005): 2162-2169.
8. Jain SR, Smith L, Brewer ED, Goldstein SL. "Non-invasive Intravascular Monitoring in the Pediatric Hemodialysis Population" Pediatri Nephrol < 18 no. 1 (2001) 15-8.